123A-locus mismatch does not adversely influence outcome following related-donor stem cell transplantation (SCT)
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چکیده
منابع مشابه
Donor Gender Does Not Affect Liver Transplantation Outcome in Children
The liver is recognized as a sex hormone-responsive organ. Gender-specific differences in liver function are known to exist. Recently, a higher failure rate for organs transplanted in adults from female donors to male recipients has been reported. This increased failure rate of livers obtainedfrom adult females and transplanted into adult males is thought to occur, at least in part, as a result...
متن کاملLimiting transplantation-related mortality following unrelated donor stem cell transplantation by using a nonmyeloablative conditioning regimen.
A nonmyeloablative conditioning regimen was investigated in 47 patients with hematological malignancy receiving allogeneic progenitor cells from matched, unrelated donors. The median patient age was 44 years. The majority of patients had high-risk features, including having failed a prior transplantation (29 individuals). Twenty of the transplants were mismatched for HLA class I and/or class II...
متن کاملUnrelated donor haemopoietic stem-cell transplantation: ATG or not?
Chronic graft-versus-host disease (GVHD) is a multisystemic syndrome involving tissue inflammation and fibrosis that shares many clinical manifestations with autoimmune diseases such as systemic lupus erythematous or systemic sclerosis. Despite being associated with lower relapse rates, chronic GVHD is the main cause of late mortality after unrelated allogeneic haemopoietic stem-cell transplant...
متن کاملInfluence of donor-recipient gender mismatch on graft function and survival following lung transplantation.
OBJECTIVES In current practice, donors and recipients are not matched for gender in lung transplantation. However, some data have suggested a possible effect of gender combinations on lung transplant outcomes. We examined whether donor-recipient (D/R) gender mismatch is related to adverse outcomes after lung transplantation in terms of early and long-term graft function and survival. METHODS ...
متن کاملLong-term outcome following cyclosporine-related neurotoxicity in paediatric allogeneic haematopoietic stem cell transplantation
With increasing numbers of children and adults undergoing allogeneic haematopoietic stem cell transplantation (HSCT), neurotoxicity is emerging as an important cause of transplant-related morbidity. The calcineurin inhibitor cyclosporine A (CI CSA) is the most frequently used agent for prevention of GvHD in both adult and paediatric patients. CSA is an established cause of posttransplantation c...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2003
ISSN: 1083-8791
DOI: 10.1016/s1083-8791(03)80124-6